4-Hydroxychalcone Induces Cell Death via Oxidative Stress in <i>MYCN</i>-Amplified Human Neuroblastoma Cells

<div>4HC enhances cytotoxicity induced by doxorubicin and cisplatin in SK-N-BE (2) and IMR-32 cells. (a–c) Cell viability measured by MTT assay and (d) representative photomicrographs of (a) SK-N-BE (2) and (b) IMR-32 treated with 5 <i>μ</i>M 4HC and (c) SH-SY5Y cells treated with 25 <i>μ</i>M 4HC, or with 5 <i>μ</i>M doxorubicin (Dox) or 100 <i>μ</i>M cisplatin (CP) with or without 4HC for 24 h. 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: 4-Hydroxychalcone Induces Cell Death via Oxidative Stress in <i>MYCN</i>-Amplified Human Neuroblastoma Cells 

Oxidative Medicine and Cellular Longevity

4-Hydroxychalcone Induces Cell Death via Oxidative Stress in MYCN-Amplified Human Neuroblastoma Cells

Figure 7