Rosiglitazone Suppresses Calcium Oxalate Crystal Binding and Oxalate-Induced Oxidative Stress in Renal Epithelial Cells by Promoting PPAR-<i>γ</i> Activation and Subsequent Regulation of TGF-<i>β</i>1 and HGF Expression

<div>(a) The formation of calcium oxalate crystals in different groups was observed by color Doppler ultrasound (red arrow indicates the stone). (b, c) Effect of RSG on the MDA level and SOD activity in renal tissue on days 7 and 14, respectively. (d–f) Protein expression <i>in vivo</i> was detected by Western blotting. (g) The expression of PPAR-<i>γ</i> in cytoplasm and nucleus was detected by Western blotting <i>in vivo</i>. The data shown are representative of at least three independent experiments. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Rosiglitazone Suppresses Calcium Oxalate Crystal Binding and Oxalate-Induced Oxidative Stress in Renal Epithelial Cells by Promoting PPAR-<i>γ</i> Activation and Subsequent Regulation of TGF-<i>β</i>1 and HGF Expression 

Figure 4 | Rosiglitazone Suppresses Calcium Oxalate Crystal Binding and Oxalate-Induced Oxidative Stress in Renal Epithelial Cells by Promoting PPAR-γ Activation and Subsequent Regulation of TGF-β1 and HGF Expression 