Sex-Specific Negative Association between Iron Intake and Cellular Aging Markers: Mediation Models Involving TNFα

Table 3

coefficients and 95% CIs of multiple linear regression analysis of iron intake and cellular aging markers, TNFα, and SOD.

Parameters	Women			Men
		95% CI			95% CI
LTL
Model 1	−0.213	(−0.308, −0.117)	<0.001	−0.068	(−0.213, 0.077)	0.357
Model 2	−0.196	(−0.296, -0.096)	<0.001	−0.102	(−0.251, 0.047)	0.177
Log2 (mtDNAcn)
Model 1	0.024	(−0.060, 0.109)	0.571	−0.123	(-0.231, −0.015)	0.026
Model 2	0.054	(−0.032, 1.141)	0.217	−0.114	(−0.223, −0.005)	0.04
TNFα
Model 1	1.944	(0.694, 3.193)	0.002	1.856	(0.137, 3.575)	0.035
Model 2	1.535	(0.264, 2.807)	0.018	1.947	(0.151, 3.742)	0.034
SOD
Model 1	0.542	(−1.991, 3.067)	0.674	4.108	(1.266, 6.950)	0.005
Model 2	0.995	(−1.469, 3.459)	0.427	4.238	(1.033, 7.444)	0.01

Model 1 only adjusted for age; model 2 adjusted for age, hypertension status, BMI, and HbA1c, LnTG, HDL-C, and carbohydrate proportion.