Research Article

A Proteomic Network Approach across the Kidney Stone Disease Reveals Endoplasmic Reticulum Stress and Crystal-Cell Interaction in the Kidney

Figure 1

Network analysis of a kidney stone. A flowchart of network construction and a GO analysis (a). The primary kidney stone PPI network was constructed from protein sets obtained from PolySearch and a proteomics data by Wright et al. [13], which consisted of 340 nodes connected via 740 edges (b). The backbone kidney stone PPI network was derived from the primary kidney stone PPI network, which consisted of 31 nodes connected via 51 edges (c). Bigger nodes represent genes with more links.
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