Tetrahydroxystilbene Glucoside Ameliorates Infrasound-Induced Central Nervous System (CNS) Injury by Improving Antioxidant and Anti-Inflammatory Capacity

Figure 5

The effects of THSG on infrasound-induced neuron apoptosis of hippocampus (HIP) region in the mouse model. The results were analyzed from three aspects. Quantity: the control (a, b) and THSG (e, f) groups had more neurons than the model group (c, d). Shape: the shapes of cells in the control group (a, b) were rounder than the model group (c, d), and the cells in the THSG group (e, f) also had a more perfect shape than the model group (c, d). Definition: big cells, staining cytoplasm, loose chromatin, and prominent nucleoli were showed in the control group (a, b) while small cells and condensed or even no staining cytoplasts were observed in the model group while the situation became better in the THSG group. Nissl bodies (chromatin granules) stand for the activity of protein synthesis and showed in red arrows and are lacking in necrotic cells. for each group.