Abatacept: A Promising Repurposed Solution for Myocardial Infarction-Induced Inflammation in Rat Models

<div>Effect of Abatacept on Apoptosis in IR injury model of myocardial infarction. (a) Immunohistochemical analysis of bax, Bcl−2 and Caspase−3; (b) immuno-blot analysis of bax, Bcl-2, Caspase-3, and Bcl-2/Bax ratio. (c) TUNEL assay. 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IR-C, ischemia-reperfusion control; Telmi10+IR, telmisartan 10 mg/kg+ischemia reperfusion; ABT5+IR, Abatacept 5 mg/kg+ischemia reperfusion; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.</div>

Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Abatacept: A Promising Repurposed Solution for Myocardial Infarction-Induced Inflammation in Rat Models 