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Antioxidants and Anti-inflammatory Compounds in Sarcopenia and Muscle Metabolism

Call for Papers

Sarcopenia is defined as an aging-related muscle dysfunction marked by gradual morphological alterations and loss of muscle mass and strength. This debilitating process affects the ability of older adults to perform daily tasks leading to a reduced quality of life. Although the proper mechanism remains to be elucidated, sarcopenia has been associated to hormonal changes, insulin resistance, inflammation, nutrition, and exercise. Among these factors, exercise promotes numerous adaptations in skeletal muscle that may help to prevent or reverse sarcopenia. Interestingly, abnormal production of reactive oxygen/nitrogen species has been associated with several myopathies/myalgias. Therefore, antioxidants and anti-inflammatory agents alter the redox balance in muscles and could then inhibit pathological processes associated to oxidative stress. The purpose of this special issue is to highlight the effects of antioxidants and anti-inflammatory agents on muscle metabolism and sarcopenia.

We invite investigators to contribute review and original research articles that will provide a better understanding of the molecular mechanisms, metabolic effects, and health benefits from muscle-targeted antioxidant/anti-inflammatory treatments. We are also interested in articles describing new approaches, innovative strategies, and synergism between antioxidant/anti-inflammatory compounds. Potential topics include, but are not limited to:

  • Relationship between oxidative stress, inflammation, exercise, and sarcopenia
  • Molecular mechanisms of antioxidants/anti-inflammatory action in immune cells and muscle tissues
  • The effect of redox balance and structural alterations in aging muscles
  • Synergistic effects of antioxidants and/or anti-inflammatory compounds on muscle senescence
  • Special interest on micronutrients, such as tocopherols, carotenoids, and omega 3/6 fatty acids
  • Latest technologies for antioxidants/anti-inflammatory administration in targeted muscles

Before submission, authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/omcl/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/omcl/sarc/ according to the following timetable:

Manuscript DueFriday, 24 January 2014
First Round of ReviewsFriday, 18 April 2014
Publication DateFriday, 13 June 2014

Lead Guest Editor

  • Marcelo Paes de Barros, Institute of Physical Activity and Sports Sciences (ICAFE) Cruzeiro do Sul University, 01506000 São Paulo, SP, Brazil

Guest Editors

  • Brian Bandy, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada S7N 5C9
  • Elaine Hatanaka, Institute of Physical Activity and Sports Sciences (ICAFE), Cruzeiro do Sul University, 01506000 São Paulo, SP, Brazil
  • Tácito Pessoa Souza-Junior, Department of Physical Education, Federal University of Parana (UFPR), 80215370 Curitiba, PR, Brazil
  • Maísa Ribeiro Pereira Lima Brigagão, Departamento de Ciências Exatas, Federal University of Alfenas (UNIFAL), 37130000 Alfenas, MG, Brazil