Hydrogen Sulfide: Biogenesis, Physiology, and Pathology
1National University of Singapore, Singapore
2University of Notre Dame, Notre Dame, USA
3Fudan University Shanghai Medical College, Shanghai, China
Hydrogen Sulfide: Biogenesis, Physiology, and Pathology
Description
Hydrogen sulfide (H2S) is an endogenous biological mediator. The physiological importance of H2S became recognized in the last two decades. It has been demonstrated that H2S mediates many physiological functions in various biological systems including cardiovascular, central nervous and reproductive systems, kidneys, and lungs. Alteration of endogenous H2S production was found in various diseases. Exogenous application of H2S may protect cell function against ischemic and oxidant injuries. Recent advances in biology and medicine indicate that H2S and its generating enzymes could be new targets to treat human diseases.
We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the biogenesis, metabolism, and biological functions of H2S and other related sulfide-containing compounds.
Potential topics include, but are not limited to:
- Recent development in biosynthesis and metabolism of H2S
- Advances in physiological and pathological functions of H2S
- New methods for detection of endogenous and exogenous H2S
- Interaction among different gaseous mediators
- Biological functions of polysulfide and SO2
- Current understanding of protein sulfhydration
- Signaling mechanisms underlying the H2S functions
- New development in H2S releasing compounds
- Prospect of sulfide-containing compounds and H2S synthesis inhibitors as therapeutic drugs