Aging in humans is related to accumulation of diverse factors such as physiological and social changes leading to decrease in many abilities, although expanding of wisdom may occur. Aging is a remarkable section of all human lives impacting on the capacity of growth and development of countries and communities. It is estimated that about 100,000 people worldwide die every day due to age-related diseases. There are many factors which impact on lifestyle-related illnesses including diet, alcohol consumption, cigarette smoking, and stress. The identification of such risk factors and reduction of their effects is an important step in overcoming aging diseases and building a healthy lifestyle. When we focus on molecular levels, lifestyle factors are tightly correlated with the concepts of oxidative stress, those underlying optimum diet, and the cellular effects elicited by micronutrients and antioxidants, as key components in achieving healthy and successful aging. Although the principal mechanisms involved are still less explored, there are lots of evidence guiding to reactive oxygen species (ROS) as one of the hallmarked parameters involved in aging. The “oxidative stress theory” states that critical aspects of the aging might be results of an irreversible accumulation of oxidative hurts and point toward physiological function, high incidence of disease, and a reduction in life span. However, a direct cause-and-effect relationship between the accumulation of oxidative-mediated injuries and aging has not been clearly established.

Now, we invite researchers and scientists to contribute original research articles as well as review articles that will encourage continuing attempts and endeavors to clear not only the pathophysiology of oxidative damages in aging but also to expand the knowledge and strategies to treat or prevent aging-related diseases. Especially, articles describing the new finding on the role of oxidative stress in initiation and development of aging process are welcome. Potential topics include, but are not limited to:

• Recent progresses on molecular aspects of therapy and/or prevention of aging-related diseases
• Recognition of characteristic risk factors associated with oxidative damage in aging-related illnesses
• Systems aging and role of free radicals
• In vitro and in vivo models to characterize mechanisms of aging and aging-related diseases
• The role of antioxidants and micronutrients in prevention and management of aging-related diseases
• New strategies in drug discovery and development of antioxidants for prevention of aging related diseases

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/oximed/osa/ according to the following timetable: