Experimental and Clinical Therapeutic Hypothermia

Call for Papers

Hypothermia has been known as a possible therapeutic tool for millennia. However, it has only been used more systematically in the last two centuries, and it is recently that we have started to understand some of its mechanisms of action and side effects including the generation of free radicals. Although recent studies on hypothermia are numerous, many questions remain unanswered, such as what is the adequate target temperature, how fast should the patient be cooled, or how fast should rewarming take place. In the evaluation of the benefits versus adverse effects of hypothermia, it is clear that the outcome depends on the conditions applied and on the pathology treated.

We invite investigators to contribute original research articles as well as review articles that explore the experimental and clinical aspects on the use of hypothermia as a therapeutic tool. Potential topics include, but are not limited to:

• Physiological effects of hypothermia
• Biological lessons from hibernation, ischemia, and reperfusion
• Simulating hypothermia with pharmacologic agents
• Augmenting hypothermia with pharmacological agents
• Organ preservation and organ specific hypothermia
• Hypothermia used as an anticonvulsant therapy
• Methods of hypothermia induction
• The impact of hypothermia on free-radical induction and oxidative stress
• Hypothermia protection against ischemia/reperfusion injury
• Clinical applications of hypothermia in neurological and cardiac injury
• Hypothermia-drug interactions
• Common complications in the use of therapeutic hypothermia
• Measuring the effectiveness of clinical hypothermia

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/oximed/ecth/ according to the following timetable:

Lead Guest Editor

• Teresa Carbonell, Department of Physiology and Immunology, University of Barcelona, Catalonia, Barcelona, Spain

Guest Editors

• Lance B. Becker, The Center for Resuscitation Science, Department of Emergency Medicine, University of Pennsylvania Health System, Philadelphia, PA, USA
• Hyung Soo Han, Department of Physiology, Brain Science and Engineering Institute, Kyungpook National University School of Medicine, Daegu, Korea
• Zinchuk V., Department of Physiology, Grodno State Medical University, Grodno, Byelarus