Prostate Cancer / 2011 / Article / Tab 4 / Clinical Study
Racial/Ethnic Patterns in Prostate Cancer Outcomes in an Active Surveillance Cohort Table 4 Multivariable Cox proportional hazards model predicting overall survival in a cohort of subjects with prostate cancer (CaP) followed on active surveillance (AS) for primary treatment, stratified by secondary treatment type.
Secondary treatment type characteristic None (AS only) RP3 EBRT-Br4 HT5 HOR1 (95% CI2 ) P valueHOR (95% CI) P valueHOR (95% CI) P valueHOR (95% CI) P valueAge at diagnosis, years 0.1737 0.1532 0.3743 0.4236 <60 Referent — Referent — Referent — Referent — 60–60.9 2.43 (0.84–6.97) 0.0983 1.65 (0.35–7.60) 0.5196 1.35 (0.45–4.02) 0.5836 1.84 (0.40–8.27) 0.4264 ≥70 2.700 (0.95–7.64) 0.0616 4.41 (0.85–22.7) 0.0762 1.84 (0.62–5.42) 0.2663 1.32 (0.30–5.74) 0.7108 Race White Referent — Referent — Referent — Referent — Black 1.24 (0.74–2.07) 0.4120 0.46 (0.09–2.32) 0.3522 1.14 (0.64–2.03) 0.6478 1.17 (0.60–2.29) 0.6282 Comorbidities 0.3218 0.4464 0.0061 0.5145 0 Referent — Referent — Referent — Referent — 1 1.15 (0.66–1.99) 0.6059 2.42 (0.65–8.99) 0.1865 0.58 (0.27–1.23) 0.1582 1.06 (0.53–2.12) 0.8657 2 1.60 (0.85–3.02) 0.1425 0.97 (0.19–4.84) 0.9731 0.48 (0.21–1.06) 0.0724 1.22 (0.60–2.46) 0.5730 ≥3 1.53 (0.86–2.71) 0.1431 2.05 (0.33–12.6) 0.4361 1.70 (0.82–3.53) 0.1518 0.71 (0.34–1.50) 0.3800 D’Amico et al. risk strata <0.0001 0.0353 0.0007 0.0787 Low Referent — Referent — Referent — Referent — Intermediate 1.47 (0.88–2.45) 0.1371 1.78 (0.44–7.12) 0.4124 2.16 (0.99–4.71) 0.0528 1.75 (0.87–3.51) 0.1112 High 3.52 (2.18–5.69) <0.0001 5.64 (1.48–21.4) 0.0110 4.20 (1.98–8.90) 0.0002 2.03 (1.09–3.78) 0.0257 Dx6 to secondary treatment, months — — 1.00 (0.97–1.03) 0.8635 0.98 (0.97–1.00) 0.0424 0.98 (0.975–0.99) 0.0010
1 HOR: hazard Odds Ratio. 2 CI: confidence Interval. 3 RP: radical prostatectomy. 4 EBRT-BR: external beam radiation therapy and Brachytherapy, combined. 5 HT: hormone therapy. 6 Dx: diagnosis of CaP.