Metastasis Update: Human Prostate Carcinoma Invasion via Tubulogenesis
Figure 3
Progressive morphological features of tubulogenesis in human prostate cancer. (a) is a tissue section stained with H&E X 200 and shows the transition of a normal prostate gland (N) to high-grade PIN (P) which has budded into invasive low-grade carcinoma (Ca). (b) is a tissue section stained with H&E X 400 demonstrating a prostate gland showing an early bud (arrows) of atypical cells. Note the absence of basal cells in the budding lesion.
