Prostate Cancer / 2011 / Article / Tab 1 / Review Article
Frequency of Positive Surgical Margin at Prostatectomy and Its Effect on Patient Outcome Table 1 Comparison of PSM rates by technical approach.
First author, yr No. of pts Cohort years Median f/u, yr Open Laparoscopic Robotic Failure rate if PSM PSM rate
valuePSM rate HR,
val. PSM rate HR,
val. Williams 2010 [7 ] 4240 2004–2006 20.1% 17.4% 17.4% Coelho 2010 [8 ] ≥250†† 1994–2009 24.0% 21.3% 13.6% Sciarra 2010 [9 ] 200 2003–2007 18% anterograde, 14% retrograde
— — — Williams 2010 [10 ] 950 2005–2008 7.6% 13.5%, HR 1.9*,
— — Coelho 2010 [11 ] 876 2008-2009 — — pT2, 6.8%, pT3, 34.0%
— Guru 2009 [12 ] 480 2005–2008 — — 5% apical, 2% versus 8%** — Bong 2009 [13 ] 301 1994–2006 2.0 24.7% at 1 institution but 4.2% at another
***
— — 25.6% at 1 institution but 100% at other Hakimi 2009 [14 ] 150 2001–2008 13.7% 12% 6.7% versus 5.3%
Laurila 2009 [15 ] 192 2006 14% — 13%
, no diff in apical margin— Terakawa 2008 [16 ] 137 2000–2007 PSM Not signif. — More multiple PSM, get # — Smith 2007 [17 ] 400 2002–2006 35%† — 15%
— Silva 2007 [18 ] 179 1999–2003 41.6% — 24.44%
— Touijer 2007 [19 ] 1177 2003–2005 11.0%; pT2 5.3%, pT3 22.0% 11.3%; pT2 8.2%; pT3 17.2% HR 1.2,
— —
*OR falls to 1.6 if nerve-sparing is eliminated as a variable
.
**Lower rate achieved by cold incision of the dorsal venous complex before suture ligation.
***For the same surgeon; but higher average pathologic stage at the first institution. † But open method was used for more high-risk cases and also cases with a higher preoperative PSA,
. †† Review of several papers.