Role of Heparan Sulfate 2-O-Sulfotransferase in Prostate Cancer Cell Proliferation, Invasion, and Growth Factor Signaling

Table 1

2OST is overexpressed in prostate carcinoma compared to normal tissue. The Oncomine concept “Prostate Carcinoma versus Normal—Top 10% Overexpressed” was queried in Oncomine (https://www.oncomine.org/). 2OST (HS2ST1) was significantly overexpressed in three different expression studies.

Prostate Carcinoma versus Normal—Top 10% Overexpressed
Study	Fold change	𝑃 value
Varambally prostate	3.43	0.015
Luo prostate 2	1.8	0.003
Liu prostate	1.413	0.002