Research Article

Histone Deacetylase Inhibitors Restore Cell Surface Expression of the Coxsackie Adenovirus Receptor and Enhance CMV Promoter Activity in Castration-Resistant Prostate Cancer Cells

Figure 5

Caspase-3/7 activity in C4-2b cells. C4-2b cells were left uninfected or were transduced with 10 MOI of AdGFP or AdTRAIL in the absence or presence of MS-275 (b) or 10 ng/mL romidepsin (a). Caspase-3/7 activity was determined at 48 hours. Data shown are the mean ± SD of an assay performed in triplicate.
137163.fig.005a
(a)
137163.fig.005b
(b)