Histone Deacetylase Inhibitors Restore Cell Surface Expression of the Coxsackie Adenovirus Receptor and Enhance CMV Promoter Activity in Castration-Resistant Prostate Cancer Cells

Figure 8

The effect of HDACi on GFP intensity in C4-2b cells. Cells were plated overnight and exposed to 10 MOI AdGFP in the presence or absence of 100 ng/mL Romidepsin or 10 μM MS-275. The geometric mean fluorescence intensity within GFP-positive cells is expressed as a fold change relative to LNCaP cells. Data shown are the Mean ± SD from three experiments.