Table 1: End-point comparisons for TRAMP GTG male mice§.

Final body weight (g) Age at tumor palpation (weeks) Age at death (weeks) GUT weight (g)Tumor differentiation Percent with metastasis
WellModeratePoor

GTG-6
 Obese ( )51.78 ± 5.30a27.67 ± 4.91 ( )35.75 ± 4.596.23 ± 1.4050%25%25%25%
 Lean ( )36.07 ± 3.75b22.0 ± 3.51 ( )28.33 ± 8.846.30 ± 1.9633%067%67%
 PBS ( )36.92 ± 1.33b29.36 ± 1.61 ( )38.33 ± 1.927.84 ± 0.8460%7%33%47%
GTG-26
 Obese ( )48.61 ± 2.60a33.38 ± 0.9442.13 ± 1.229.10 ± 1.54 ( )50%50%013%
 *Lean ( )39.08 ± 2.46b33.50 ± 1.0943.00 ± 1.678.90 ± 1.45 ( )60%20%020%
 PBS ( )36.65 ± 1.63b32.30 ± 1.1041.30 ± 1.408.16 ± 1.0 ( )58%8%33%33%

§columns with different letters indicate a significant difference among the groups.
*pathology report not received for one mouse in this group.