Recent Trends in Prostate Cancer Incidence by Age, Cancer Stage, and Grade, the United States, 2001–2007

Table 3

Incidence rates and annual percentage changes in rates for prostate cancer by cancer stage and grade, US men, 2004–2007.

	Count	%	Rate^1	95% CI		APC	95% CI
Total^2	751,565	100.0	145.3	144.9	145.6	1.9	−3.4	7.5
Stage^3
Localized	613,170	81.6	118.7	118.4	119.0	2.3	−3.2	8.1
Regional	75,412	10.0	13.7	13.6	13.8	1.8	−4.5	8.6
Distant	23,455	3.1	4.8	4.7	4.9	−3.2	−8.0	1.8
Unstaged	39,503	5.3	8.1	8.0	8.2	−0.2	−1.6	1.1
Grade
Well differentiated	8,618	1.1	1.7	1.7	1.7	−25.5	−29.5	−21.2
Moderately differentiated	368,482	49.0	70.3	70.0	70.5	−1.8	−6.6	3.2
Poorly differentiated	348,426	46.4	68.0	67.8	68.2	6.8	1.3	12.7
Undifferentiated, anaplastic	3,212	0.4	0.6	0.6	0.7	1.0	−7.3	9.9
Unknown	22,827	3.0	4.7	4.6	4.7	1.1	−9.3	12.6
Localized
Well differentiated	7,714	1.3	1.5	1.5	1.6	−24.5	−26.4	−22.5
Moderately differentiated	333,625	54.4	63.7	63.4	63.9	−1.3	−6.1	3.7
Poorly differentiated	259,719	42.4	51.1	50.9	51.3	8.0	2.0	14.3
Undifferentiated, anaplastic	1,939	0.3	0.4	0.4	0.4	6.3	−5.5	19.7
Unknown	10,173	1.7	2.0	2.0	2.1	0.2	−16.0	19.6
Regional
Well differentiated	210	0.3	0.0	0.0	0.0	−23.8	−42.3	0.7
Moderately differentiated	16,449	21.8	2.9	2.9	3.0	−10.9	−17.6	−3.8
Poorly differentiated	57,506	76.3	10.5	10.4	10.6	6.1	0.6	11.8
Undifferentiated, anaplastic	656	0.9	0.1	0.1	0.1	−6.7	−21.4	10.7
Unknown	591	0.8	0.1	0.1	0.1	−6.8	−32.1	28.0
Distant
Well differentiated	95	0.4	0.0	0.0	0.0	−13.7	−46.2	38.3
Moderately differentiated	1,903	8.1	0.4	0.4	0.4	−18.6	−28.2	−7.8
Poorly differentiated	17,376	74.1	3.5	3.5	3.6	−1.6	−6.6	3.7
Undifferentiated, anaplastic	451	1.9	0.1	0.1	0.1	−8.2	−30.0	20.5
Unknown	3,630	15.5	0.8	0.7	0.8	−1.4	−10.2	8.4
Unstaged
Well differentiated	599	1.5	0.1	0.1	0.1	−38.7	−60.4	−4.9
Moderately differentiated	16,488	41.7	3.3	3.2	3.3	−1.0	−2.4	0.4
Poorly differentiated	13,818	35.0	2.9	2.8	2.9	0.4	−2.7	3.7
Undifferentiated, anaplastic	166	0.4	0.0	0.0	0.0	−5.0	−35.0	38.8
Unknown	8,432	21.3	1.8	1.7	1.8	3.6	−5.4	13.4

APC: annual percentage change, CI: confidence interval.
¹Rates are per 100,000 men and are age-adjusted to the 2000 US standard population.
²Data are from 46 population-based cancer registries that participate in the National Program of Cancer Registries (NPCR) and/or the Surveillance, Epidemiology, and End Results (SEER) Program and meet high quality data criteria. These registries cover 93.5% US population for 2004–2007.
³Sum of counts is less than total due to missing information on stage.