Table 4: Univariate and multivariate analysis of factors for detecting apex cancer among clinicopathological factors.

True positive 
False negative Univariate analysis Multivariate analysis
value 95% CI

Age, mean years 65.2 65.30.898
BMI, mean kg/m222.4 22.6 0.677
PSA, mean ng/mL 9.69 8.10 0.113
F/T ratio, mean %12.8 16.4 0.024*0.953–1.100 0.737
Prostate volume, mean mL 32.1 32.5 0.890
Clinical T stage
 T1c50 40
 T2a–c12 120.954
T3a3 1
Biopsy Gleason score
 6 20 24
 7 8 41 270.197
 9 10 4 2
Positive core number, mean3.66 2.43 0.0002*0.574–1.133 0.215
pathological T stage
 T2a–c33 390.010 0.234–2.632 0.696
T3a32 14
RP apex Gleason score
 6 13 13
 7 8 46 350.431
 9 10 6 5
Apex tumor volume, mean mL0.802 0.193 <0.0001*0.004–0.192 0.0002*
Total tumor volume, mean mL 2.76 1.76 0.016*0.572–1.001 0.051

True positive: RP specimen positive and biopsy positive, false negative: RP specimen positive and biopsy negative, BMI: body mass index, PSA: prostate specific antigen, F/T: free total PSA ratio, RP: radical prostatectomy, *statistically significant.