Research Article
Quantifying the Ki-67 Heterogeneity Profile in Prostate Cancer
Table 1
Patient characteristics.
| | Total | NCCN low | NCCN inter | NCCN high |
| Number of patients | 77 | 31 | 30 | 16 | Mean age (years) | 66.8 | 65.7 | 65.8 | 70.6 | Age range | 44–82 | 44–76 | 51–82 | 58–82 | Mean PSA (ng/dL) | 7.7 | 4.9 | 7.22 | 14.1 | PSA range | 0.51–36.2 | 0.51–9.7 | 0.8–15 | 2.3–36.2 | T1A-C | 63 (82%) | 30 (97%) | 28 (93%) | 5 (31%) | T2A | 14 (18%) | 1 (3%) | 2 (7%) | 11 (69%) | T2B+ | 0 | 0 | 0 | 0 | Gleason 6 | 34 (44%) | 31 (100%) | 3 (10%) | 0 | Gleason 7 | 27 (35%) | 0 | 27 (90%) | 0 | Gleason 8–10 | 16 (21%) | 0 | 0 | 16 (100%) | Biopsy-positive cores with Ki-67 stain | 268 | 66 | 105 | 97 | Mean cores per patient | 3.48 | 2.13 | 3.50 | 6.06 | Intraprostatic: patients with ≥2 Ki-67 values | 47 | 16 | 19 | 12 | Intralesion: lesions with ≥2 MRI targeted cores | 38 | 7 | 15 | 16 |
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