Quantifying the Ki-67 Heterogeneity Profile in Prostate Cancer

Table 1

Patient characteristics.

	Total	NCCN low	NCCN inter	NCCN high
Number of patients	77	31	30	16
Mean age (years)	66.8	65.7	65.8	70.6
Age range	44–82	44–76	51–82	58–82
Mean PSA (ng/dL)	7.7	4.9	7.22	14.1
PSA range	0.51–36.2	0.51–9.7	0.8–15	2.3–36.2
T1A-C	63 (82%)	30 (97%)	28 (93%)	5 (31%)
T2A	14 (18%)	1 (3%)	2 (7%)	11 (69%)
T2B+	0	0	0	0
Gleason 6	34 (44%)	31 (100%)	3 (10%)	0
Gleason 7	27 (35%)	0	27 (90%)	0
Gleason 8–10	16 (21%)	0	0	16 (100%)
Biopsy-positive cores with Ki-67 stain	268	66	105	97
Mean cores per patient	3.48	2.13	3.50	6.06
Intraprostatic: patients with ≥2 Ki-67 values	47	16	19	12
Intralesion: lesions with ≥2 MRI targeted cores	38	7	15	16