Role of p73 Dinucleotide Polymorphism in Prostate Cancer and p73 Protein Isoform Balance

Table 4

Summary of association studies of p73 DNP in various cancer sites¹.

Site	Population	Case/control	OR (95% CI)	Reference
Bladder	Indian	200/200	1.54 (1.02–2.33)	[6]
Breast	Chinese	170/178	0.77 (0.50–1.19)	[7]
Breast	Chinese	170/0	2.76  (𝟏.𝟏𝟕--𝟔.𝟒𝟗)^2	[8]
Breast	Japanese	200/282	0.82 (0.57–1.19)	[9]
Breast	France white	59/34	2.46 (0.92–6.58)	[10]
Cervical	Portuguese	176/141	1.01 (0.63–1.62)	[11]
Cervical	Japanese	112/442	1.51 (1.00–2.30)	[12]
Colorectal	Japanese	147/235	0.85 (0.56–1.29)	[13]
Colorectal	Tunisian	150/204	1.09 (0.71–1.66)	[14]
Colorectal	Korean	383/469	1.50 (1.14–1.96)	[15]
Colorectal	Swedish	179/260	0.92 (0.53–1.53)	[16]
Endometrial	Japanese	114/442	1.36 (0.90–2.06)	[17]
Esophageal	Chinese	348/630	1.02 (0.78–1.34)	[18]
Esophageal	Japanese	102/235	0.64 (0.40–1.04)	[13]
Esophageal	UK whites	84/152	0.90 (0.53–1.53)	[19]
H&N	US white	708/1229	1.31 (1.09–1.58)	[20]
H&N	Italian	283/295	1.36 (0.95–1.93)	[21]
H&N	US whites	326/349	1.06 (0.78–1.45)	[22]
Oral	Indian	303/319	2.38 (1.73–3.29)	[23]
Oropharyngeal	US mixed	309/0	2.10  (𝟏.𝟐𝟎--𝟑.𝟖𝟎)^2,3	[24]
Gastric	Italian	114/295	0.94 (0.58–1.54)	[25]
Gastric	Japanese	144/235	0.88 (0.58–1.34)	[13]
Liver	Chinese	476/526	2.19  (𝟏.𝟐𝟓--𝟑.𝟖𝟑)^4	[26]
Lung	Chinese	293/380	1.48 (1.08–2.02)	[27]
Lung	US white	1054/1139	1.34 (1.13–1.59)	[28]
Lung	Chinese	425/588	0.67 (0.52–0.86)	[29]
Lung	Korean	582/582	1.13 (0.90–1.43)	[30, 31]
Lung	US white	863/852	1.34 (1.10–1.64)	[32]
Lung	Japanese	189/235	0.91 (0.62–1.34)	[33]
Lymphoma	Japanese	103/440	1.61 (1.04–2.47)	[34]
Melanoma	Whites	805/838	1.05 (0.86–1.28)	[35]
Ovary	Chinese	257/257	0.81 (0.95–1.18)	[36]
Prostate	Indian	177/265	1.21 (0.80–1.86)	[37]

1Analysis is based on dominant model (AT/AT + GC/AT versus GC/GC).
²Cases only.
³HPV16+ versus HPV16−.
⁴HbsAg-positive individuals.