Review Article
CHEK2∗1100delC Mutation and Risk of Prostate Cancer
Table 2
Characteristics and results of 7 excluded prostate cancer studies.
| Carrier/Total | Population | Country | OR/HR (95% CI) | value | Ref. |
| 14/1,864 | Unselected cases | PL | 3.5 (1.6–7.5) | 0.002 | [25, 26] | 3/249 | Familial cases | | 5.6 (1.6–19.9) | 0.02 | | 12/5,496 | Controls | | Reference | | |
| 3/84 | Cases | US | NA | NA | [27, 28] |
| | Families with breast cancer history | UK, NE, DE, US | 2.68 (ratio of carrier RR versus noncarrier RR) | 0.26 | [29] |
| 3/690 | Unselected cases | PL | 2.1 (0.5–9.4) | 0.32 | [30] | 1/98 | Familial cases | | 4.9 (0.5–44.6) | 0.11 | | 4/1,921 | Controls | | Reference | | |
| 3/690 | Unselected cases | PL | 1.74 (0.48–6.35) | 0.39 | [31] | 10/4,000 | Controls | | Reference | | |
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PL: Poland, UK: United Kingdom, NE: Netherlands, DE: Denmark, US: United States, NA: not available.
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