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Prostate Cancer

Volume 2014 (2014), Article ID 640859, 1 page

http://dx.doi.org/10.1155/2014/640859
Erratum

Erratum to “Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study”

1Department of Urology, Jules Bordet Institute, 1 Héger-Bordet Street, 1000 Brussels, Belgium

2Université Libre de Bruxelles, 50 Franklin Roosevelt Avenue, 1050 Brussels, Belgium

3Department of Radiology, Jules Bordet Institute, 1 Héger-Bordet Street, 1000 Brussels, Belgium

Received 16 April 2014; Accepted 27 April 2014; Published 30 April 2014

Copyright © 2014 Roland Van Velthoven et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The following abstract should replace the abstract originally published for the article titled “Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study.”

Objectives. To present the results of a prospective phase IIa study assessing the role of primary zonal High Intensity Focused Ultrasound (HIFU) for prostate cancer treatment. Methods. 31 consecutive patients with unilateral organ confined prostate cancer primarily treated by zonal HIFU (from February 2007 to June 2011) were recruited into a single centre prospective phase IIa feasibility study. Complications were prospectively recorded and graded according to the Clavien-Dindo score. Postoperatively, patients were followed with serial serum PSA determinations and digital rectal examinations. An individual PSA nadir was identified in each patient. Followup also included whole-gland biopsies performed in the event of a PSA rising >2.0 ng/mL above nadir value (Phoenix criteria). Results. At a median followup of 38 months, biochemical recurrence-free survival was 100%, 89%, and 82.7% at 1, 2, and 3 years, respectively, with overall and cancer specific survival of 100%. The procedure was safe and well tolerated with no major adverse events. All patients were continent at their last followup and 55.2% (16/29) had erectile function sufficient for penetration. Conclusion. Primary zonal HIFU is a valid focal therapy strategy, safe and feasible in day to day practice with good promising results.