Assessment of the Performance of Magnetic Resonance Imaging/Ultrasound Fusion Guided Prostate Biopsy against a Combined Targeted Plus Systematic Biopsy Approach Using 24-Core Transperineal Template Saturation Mapping Prostate Biopsy

Table 5

Gleason score breakdown for MRI/US-TBx and TTMB ().

Gleason score	MRI/US-TBx	TTMB	CBS	value (MRI/US-TBx versus CBS)
No cancer	40 (50%)	32 (40%)	25 (31%)
3 + 3	8 (10%)	20 (25%)	16 (20%)
3 + 4	18 (22.5%)	24 (30%)	25 (31%)
4 + 3	7 (9%)	3 (4%)	7 (9%)
4 + 4	4 (5%)	1 (1%)	4 (5%)
4 + 5	2 (2.5%)	0	2 (2.5%)
5 + 4	1 (1%)	0	1 (1.5%)
Total	80	80	80
Low risk	8 (10%)	20 (25%)	16 (20%)	0.04
Int. risk	25 (31%)	27 (34%)	32 (40%)	0.02
High risk	7 (9%)	1 (1%)	7 (9%)	Not sig

CBS = combined biopsy strategy, MRI/US-TBx = MRI/transrectal ultrasound fusion targeted biopsy, and TTMB = transperineal template guided mapping biopsy.
Low risk = GS 6, intermediate risk = GS 7, and high risk = GS 8 or greater.