Assessment of the Performance of Magnetic Resonance Imaging/Ultrasound Fusion Guided Prostate Biopsy against a Combined Targeted Plus Systematic Biopsy Approach Using 24-Core Transperineal Template Saturation Mapping Prostate Biopsy

Table 7

Sensitivity, specificity, NPV, and PPV of PI-RADS scoring system for prostate cancer detection, derived from combined biopsy strategy (MRI/US-TBx + TTMB). For this analysis PI-RADS 1/2 is considered negative and PI-RADS 3–5 is considered positive. .

	All PCa	Sign PCa	Insig PCa
Sensitivity	96	98	91
Specificity	32	22	13
NPV	75	92	83
PPV	78	56	23

PCa = prostate cancer, Sign = significant, Insig = insignificant, NPV = negative predictive value, and PPV = positive predictive value.