Research Article

Paired-Pulse Inhibition in the Auditory Cortex in Parkinson's Disease and Its Dependence on Clinical Characteristics of the Patients

Table 2

Inhibition of the second N1-P2 complex of cortical auditory evoked potentials at paired-click stimulation in age-matched control group and patients with Parkinson’s disease .

Study groupsInhibition in % of the second N1-P2Averaged
complex at interstimulus intervals
500 ms700 ms900 ms

Age-matched control;
PD patients with stage
1.5–2.0;




PD patients with stage
2.5–3.0;




All PD patients;




The inhibition was defined: ( )/A1 100, where A1 is amplitude of the first and A2 is amplitude of the second evoked potential upon paired-click auditory stimulation. ; compared to control subjects (ANOVA, Mann-Whitney U test). :-number of subjects in the investigated groups.