A Perfusion MRI Study of Emotional Valence and Arousal in Parkinson’s Disease
Table 2
Associations of valence and arousal with pharmacological status and demographic variables.
Valence
Arousal
(valence)
(arousal)
Effect of SYN115 (mean difference [unitless])
+0.08
+0.05
0.02*
0.08
26
On levodopa minus pre-levodopa (mean difference [unitless])
−0.06
−0.04
0.03*
0.18
26
Age (correlation, )
0.09
0.18
0.70
0.43
21
Hoehn and Yahr stage (correlation, )
0.22
−0.03
0.34
0.89
21
UPDRS (correlation, )
0.08
0.08
0.42
0.41
104
Sex (-test)
0.82
0.92
Male (mean)
0.33
−0.22
13
Female (mean)
0.30
−0.20
8
PD symptoms worse on which side of body? (-test)
0.25
0.34
Right (mean)
0.26
−0.17
13
Left (mean)
0.43
−0.28
*
. †21 people, 26 experiments (5 people participated twice, once for the 20 mg b.i.d. study, once for the 60 mg b.i.d. study), 4 UPDRS measurements per experiment (). ‡One subject was equally affected on left and right and was excluded from this analysis.
