Research Article

A Perfusion MRI Study of Emotional Valence and Arousal in Parkinson’s Disease

Table 3

CBF correlates with emotional valence.
(a) Clusters in the brain in which CBF correlates positively with valence

FDR-corrected valueNumber of voxelsaPeak T value (22 d.f.)Coordinates of peak T valueSide of brainAnatomical description of cluster

<10−156743.8628.5, 21, 18RightMiddle frontal gyrus (BA 8, 9), precentral gyrus, anterior cingulate (BA 32), insula, putamen, caudate
0.001763.864.5, 57, 18BilateralMedial and superior frontal gyri (BA 10, 9)
0.001973.86−58.5, 3, 21LeftPrecentral gyrus (BA 6)
0.002873.8616.5, −3, −3RightMedial globus pallidus, ventrolateral thalamus, amygdala, frontal prepiriform cortex ventral to accumbens
0.002823.86−16.5, 6, −18LeftOlfactory area, parahippocampal gyrus, medial globus pallidus/thalamus border, thalamus, hypothalamus, substantia nigra
0.053363.8528.5, 42, −9RightMiddle frontal gyrus (BA 11)
0.010563.84−46.5, −60, 33LeftAngular gyrus and inferior parietal lobule (BA 39, 40)

aEach voxel contained 0.027 mL.
(b) Clusters in the brain in which CBF correlates negatively with valence

FDR-corrected valueNumber of voxelsPeak T value (22 d.f.)Coordinates of peak T valueSide of brainAnatomical description of cluster

<0.00021173.86−34.5, −42, 66LeftSuperior parietal lobule and precuneus (BA 7), postcentral gyrus (BA 5), posterior cingulate cortex (BA 31)
<10−51783.86−13.5, 12, 3BilateralSubcallosal gyrus (BA 25), left caudate and putamen
0.007673.864.5, −75, 54RightSuperior parietal lobule and precuneus (BA 7), postcentral gyrus (BA 5)
0.020463.86−34.5, −15, 57LeftPrecentral gyrus (BA 6), postcentral gyrus (BA 3)
0.014543.8643.5, −39, 63RightInferior parietal lobule (BA 40), superior parietal lobule (BA 7), postcentral gyrus (BA 5)
0.008633.8543.5, 39, −6RightInferior frontal gyrus (BA 47)—lateral frontal part
0.020463.8525.5, −63, 6RightLingual gyrus (BA 18, 19)
0.036393.85−37.5, 33, −6LeftInferior frontal gyrus (BA 47)
0.043363.8325.5, 24, −6RightInferior frontal gyrus (BA 47)

Note: Only clusters significant after correction for multiple comparisons are shown here.