Research Article

Traditional Chinese Medicine Improves Activities of Daily Living in Parkinson's Disease

Table 2

Results of clinical evaluation between before and after test granule administration.

Placebo ( )ZAZ ( )
Week 0Week 1Week 13Week 0Week 1Week 13

UPDRS total score46.6  ±  16.344.7  ±  15.345.9  ±  18.146.3  ±  17.137.1  ±  11.2*##40.7  ±  15.1*#
 UPDRS I2.5  ±  0.72.3  ±  1.12.4  ±  1.22.6  ±  0.82.1  ±  0.7*2.3  ±  0.9
 UPDRS II15.7  ±  9.3 14.8  ±  11.215.3  ±  11.6 15.9  ±  11.312.5  ±  4.6*#13.4  ±  9.8*#
 UPDRS III25.5  ±  12.923.8  ±  10.6*24.9  ±  12.725.4  ±  10.119.3  ±  9.8*#21.6  ±  10.4*
 UPDRS IV 3.1  ±  1.12.9  ±  1.63.0  ±  1.43.2  ±  1.42.6  ±  0.8*#2.7  ±  1.3*#
Awake time (counts/min)98.5  ±  14.1102.6  ±  18.9100.7  ±  16.999.8  ±  17.8126.7  ±  13.4*##118.4  ±  11.8*##
Sleep time (counts/min)42.9  ±  17.138.8  ±  15.6*40.1  ±  14.843.2  ±  11.635.6  ±  13.6*#32.8  ±  13.6*#
α (awake time)0.97  ±  0.210.95  ±  0.280.96  ±  0.180.97  ±  0.240.88  ±  0.21*#0.86  ±  0.19*##
α (sleep-time)1.19  ±  0.281.16  ±  0.271.15  ±  0.291.18 ±  0.261.04  ±  0.22*#1.02  ±  0.18*##

Data presented are mean ± SD. * ; ** compared to week 0 (repeated-measure ANOVAs); #P ; ## compared to placebo (Bonferroni test); UPDRS: Unified Parkinson's Disease Rating Scale; α: power-law exponent.