Table 4: Total Motor UPDRS ON and OFF medication by PD subtype ( ).

PD subtype
Tremor-dominant
( ) mean (SD)
Akinetic rigid
( ) mean (SD)
Mixed
( ) mean (SD)
ANOVA
value

Total Motor UPDRS ON medication12.1 (7.8)a18.9 (11.4)b13.2 (5.1)a0.001
Total fMotor UPDRS OFF medication19.3 (9.9)a26.9 (12.1)b20.9 (5.7)a0.001
Difference between ON and OFF7.2 (5.1)a8.0 (5.4)a7.7 (1.9)a0.73
Levodopa dosage per day (mg)551.6 (306.2)a ( )613.6 (285.4)a ( )569.6 (357.6)a ( )0.54

Hoehn and Yahr–OFF medication (%) (%) (%)Chi-square -value

15 (15.2)5 (3.5)0 (0.0)0.003
1.55 (15.2)4 (2.8)3 (16.7)
214 (42.4)42 (29.6)8 (44.4)
2.55 (15.2)46 (32.4)3 (16.7)
33 (9.1)27 (19.0)4 (22.2)
41 (3.0)11 (7.8)0 (0.0)
50 (0.0)7 (4.9)0 (0.0)

UPDRS = Unified Parkinson’s Disease Rating Scale.
*One subject excluded, because they were on MAO-B inhibitors alone.
a, bMeans within a row with different letters differ significantly ( ; pairwise t-test).