Effects of Human Alpha-Synuclein A53T-A30P Mutations on SVZ and Local Olfactory Bulb Cell Proliferation in a Transgenic Rat Model of Parkinson Disease

Table 2

Measure of the width of TH innervation in the olfactory bulb glomerular layer in wild-type and transgenic rats. The width was measured in the anterior level (bregma 6.7 mm), in the median level (bregma 6.2 mm), and in the posterior level (bregma 5.7 mm) of the olfactory bulb. Mean ± SEM. **𝑃<.01; ns: no statistical difference between the 2 groups. A significant increase of the TH innervation was observed for bregma 6.2 mm level in transgenic as compared to wild type rats.

	Wild-type group	Transgenic group	𝑃<.01
Bregma: 6.7 mm	434.2±16.46	480.9±34.23	ns
Bregma: 6.2 mm	572.5±17.63	643.6±8.18	**
Bregma: 5.7 mm	684.4±51.34	701.0±48.79	ns