Review Article

Parkinson's Disease: Leucine-Rich Repeat Kinase 2 and Autophagy, Intimate Enemies

Figure 1

LRRK2 domain structure with homodimeric conformation. LRRK2 is a protein that contains ankyrin repeats, leucine-rich repeats, a catalytic core of the protein contains a GTP-binding ROC (Ras of complex proteins), COR domain (C-terminal of ROC), kinase domain. At the C-terminus is a WD40 repeat followed by a short C-terminal tail.
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