Parkinson's Disease: Leucine-Rich Repeat Kinase 2 and Autophagy, Intimate Enemies
Figure 1
LRRK2 domain structure with homodimeric conformation. LRRK2 is a protein that contains ankyrin repeats, leucine-rich repeats, a catalytic core of the protein contains a GTP-binding ROC (Ras of complex proteins), COR domain (C-terminal of ROC), kinase domain. At the C-terminus is a WD40 repeat followed by a short C-terminal tail.