Parkinson's Disease: Leucine-Rich Repeat Kinase 2 and Autophagy, Intimate Enemies

Figure 3

Molecular regulation of autophagy. In the figure, the factors that stimulate autophagy (green) are JNK, ERK1/2, ROS, or PI3K class III, whereas the inhibitory factors (red) are NF-𝜅B, mTOR, caspase 8, Bcl-2, or p38.