Review Article

Clinical Aspects and Management of Levodopa-Induced Dyskinesia

Table 2

Adjuvant therapy versus placebo.

PramipexoleRopinirolePergolide*BromocriptineCabergoline

Off-time reduction (h/day)−1.81−0.93−1.60−1.78−1.29
LEDD red (mg/day)−114.82−119.81−183.90−52.17−149.60
UPDRS ADL reduction (pts)−1.78
UPDRS III reduction (pts)−4.80−1.74
Incidence of dyskinesia (OR)2.633.214.642.521.44

*Based on data from just one trial [71].