Importance of the Brain Angiotensin System in Parkinson’s Disease

Table 3

Summary of overlapping functions associated with the AngIV/AT₄ receptor subtype and the HGF/c-Met receptor.

Function	AngIV/AT4; receptor subtype	HGF/c-Met; receptor
Memory facilitation	[30, 86–92]	[51, 53, 54, 56, 69]
Hippocampal LTP, Ca^++ signaling	[93–96]	[52]
Dendritic arborization	[97]	[98–102]
Cerebral blood flow	[36, 38, 103]	[51, 53, 54, 65, 104–106]
Seizure protection	[107–109]	[12]
Parkinson’s disease	[110]	[60–63, 70]
Angiogenesis and PAI-1 expression	[22, 83, 111, 112]	[65, 113, 114]
Neurite outgrowth	[115]	[114, 116, 117]