Research Article

Measuring Hemoglobin Levels in the Optic Disc of Parkinson’s Disease Patients Using New Colorimetric Analysis Software

Table 2

Mean and standard deviation in parenthesis of hemoglobin’s percentage analysing optic disc photographs with Laguna ONhE program (optic nerve head hemoglobin) of Parkinson’s disease patients and healthy subjects and statistical significance of the comparison between both groups ().

Healthy subjectsParkinson’s patients

Mean Hb67 (11)58 (19)0.001
Hb 174 (16)70 (16)0.251
Hb 273 (14)64 (16)0.010
Hb 368 (12)56 (14)<0.001
Hb 471 (15)65 (18)0.096
Hb 574 (13)64 (15)0.001
Hb 668 (12)58 (24)0.002
Hb 764 (17)60 (16)0.316
Hb 871 (11)60 (14)<0.001
Hb 969 (11)56 (15)<0.001
Hb 10 57 (16)54 (12)0.360
Hb 1158 (17)49 (12)0.011
Hb 1261 (13)49 (12)<0.001
Hb 1357 (17)52 (16)0.247
Hb 1454 (17)47 (16)0.032
Hb 1558 (15)46 (12)0.001
Hb 16 60 (17)57 (15)0.428
Hb 17 64 (17)57 (14)0.036
Hb 1867 (14)57 (19)0.002
Hb 1967 (19)66 (19)0.835
Hb 2077 (14)69 (16)0.005
Hb 2176 (11)65 (18)0.001
Hb 2273 (17)71 (19)0.724
Hb 2384 (13)71 (19)0.005
Hb 2475 (12)64 (17)0.001

Hb: hemoglobin. *Significant difference ( < 0.002) in Student’s -test with Bonferroni correction for multiple comparison between healthy subjects and PD patients.