Measuring Hemoglobin Levels in the Optic Disc of Parkinson’s Disease Patients Using New Colorimetric Analysis Software
Table 3
Mean and standard deviation of retinal nerve fiber layer thicknesses obtained with the Cirrus and Spectralis optical coherence tomography devices in healthy controls and patients with Parkinson’s disease.
Parameters
Healthy controls
PD patients
RNFL Cirrus measurements
Mean thickness
105 (10)
93 (10)
<0.001
Superior quadrant
139 (19)
115 (17)
0.007
Nasal quadrant
80 (11)
73 (13)
0.005
Inferior quadrant
134 (21)
119 (18)
<0.001
Temporal quadrant
66 (11)
65 (13)
0.564
Hour sector 1
118 (23)
102 (15)
0.004
Hour sector 2
101 (19)
86 (19)
0.002
Hour sector 3
64 (10)
56 (11)
0.199
Hour sector 4
75 (13)
62 (14)
0.019
Hour sector 5
117 (22)
94 (16)
<0.001
Hour sector 6
149 (24)
130 (20)
0.003
Hour sector 7
137 (26)
129 (24)
0.112
Hour sector 8
70 (15)
68 (14)
0.290
Hour sector 9
60 (10)
55 (10)
0.277
Hour sector 10
78 (15)
75 (14)
0.306
Hour sector 11
136 (23)
130 (22)
0.018
Hour sector 12
126 (22)
119 (25)
0.183
RNFL Spectralis measurements
Mean thickness
100 (10)
93 (10)
0.030
Superior quadrant
123 (13)
115 (26)
0.019
Nasal quadrant
73 (13)
71 (26)
0.667
Inferior quadrant
133 (20)
122 (27)
0.005
Temporal quadrant
71 (11)
64 (23)
0.023
Superior nasal
126 (17)
122 (18)
0.091
Inferior nasal
141 (18)
138 (18)
0.124
Inferior temporal
108 (21)
99 (18)
0.007
Superior temporal
113 (15)
103 (19)
0.002
PD: Parkinson’s disease; RNFL: retinal nerve fiber layer. *Significant difference ( < 0.003 for Cirrus measurements and < 0.006 for Spectralis measurements) in Student’s -test with Bonferroni correction between healthy subjects and PD patients.
