Rapid Screening for Cognitive Impairment in Parkinson’s Disease: A Pilot Study
Table 1
Population characteristics.
CDR = 0
CDR ≥ 0.5
Age (mean, SD)
65.02
10.09
69.97
10.27
0.02
Years of education (mean, SD)
9.95
3.75
7.72
5.72
0.02
Female (number, %)
16.00
39%
26.00
43%
0.82
Ethnicity
0.07
Chinese (number, %)
35.00
85%
44.00
73%
Malay (number, %)
2.00
5%
7.00
12%
Indian (number, %)
2.00
5%
9.00
15%
Others (number, %)
2.00
5%
0.00
0%
MMSE (mean, SD)
26.22
2.13
21.93
5.16
<0.01
MoCA (mean, SD)
24.17
2.59
16.35
5.53
<0.01
NINDS-CSN 5-minute protocol (mean, SD)
9.83
1.48
6.50
2.64
<0.01
Duration of PD (mean, SD)
4.50
4.99
6.77
5.26
0.01
UPDRS (mean, SD)
20.80
10.99
27.97
15.37
0.01
Hoehn and Yahr scale
<0.01
1.0 (number, %)
20.00
49%
20.00
33%
1.5 (number, %)
2.00
5%
1.00
2%
2.0 (number, %)
18.00
44%
15.00
25%
2.5 (number, %)
1.00
2%
8.00
13%
3.0 (number, %)
0.00
0%
12.00
20%
3.5 (number, %)
0.00
0%
3.00
5%
4.0 (number, %)
0.00
0%
1.00
2%
SEADL (mean, SD)
8.56
0.74
7.05
2.10
<0.01
Note: CDR = Clinical Dementia Rating; SD = Standard Deviation; MMSE = Mini Mental State Examination; MoCA = Montreal Cognitive Assessment; NINDS-CSN = National Institute of Neurological Disease and Stroke-Canadian Stroke Network; PD = Parkinson’s disease; UPDRS = Unified Parkinson’s Disease Rating Scale; SEADL = Schwab and England Activities of Daily Living Scale.
