The Natural History of Depression in Parkinson’s Disease within 30-Month Follow-Up

Table 3

Clinical and demographic correlates of change in HDRS.

Variation	Unstandardized Coefficients	Standardized error	Standardized Coefficients	value
Constant	3.669	1.639		2.239	0.028
HDRS baseline	−0.672	0.100	−0.631	−6.736	<0.001
UPDRS-II baseline	0.451	0.113	0.404	3.997	<0.001
UPDRS-II change	0.245	0.108	0.222	2.269	0.026
MMSE change	−0.481	0.216	−0.202	−2.230	0.029
Sex (Female = 0, Male = 1)	−4.296	1.217	−0.307	−3.529	<0.001

We include variations like age, PD duration, PD subtypes, age of onset, and others into multiple linear regression models: using stepwise regression. And model summary: , , and . was considered significant. Abbreviations: PD: Parkinson’s disease; HDRS: Hamilton Depression Rating Scale; MMSE: Mini-Mental State Examination; UPDRS-II: The Unified Parkinson Disease Rating Scale for motor; UPDRS-III: The Unified Parkinson Disease Rating Scale for Activities of Daily Living portions.