MRI Correlates of Parkinson’s Disease Progression: A Voxel Based Morphometry Study

Table 3

Grey matter reduction in PD patients with respect to controls at retest.

	Cluster	Voxel	Level	MNI coord. (mm)
R, parietal lobe (BA 40)	449	3.56	<0.001	48, , 46
R, angular gyrus (BA 39); R, precuneus (BA 31)
R, inferior parietal lobule (BA 7)
R, superior occipital gyrus (BA 19)		3.34	<0.001	39, , 31
R, putamen^*	25	3.47	<0.05	24, , 10
Midbrain^*	176	3.53	<0.05	2, ,

< 0.001 uncorrected for multiple comparisons (voxel level > 241 voxels).
^*Correction SVC = 0.05 (FWE).
L = left and R = right. BA = Brodmann area.