Association of a BACE1 Gene Polymorphism with Parkinson’s Disease in a Norwegian Population

Table 1

Genotype and allele frequencies.

Gene	SNP ID	Allele; m/M	PD	controls	Genotype frequencies ()							HWE
					Patients			Controls
					m/m	m/M	M/M	m/m	m/M	M/M
ADAM10	rs514049	a/C	183	177	32	99	52	27	93	57	0.70	0.11
	rs2305421	g/A	184	178	3	47	134	3	37	138	0.55	1.00
BACE1	rs638405	g/C	184	178	19	97	68	35	73	70	0.02	0.91
	rs11601511	c/G	184	178	4	53	127	5	48	125	0.86	1.00
BACE2	rs12149	c/T	184	178	48	90	46	41	86	51	0.68	0.60
	rs2252576	t/C	184	178	15	67	102	15	62	101	0.96	0.17
PSEN2	rs1295652	a/G	184	178	7	60	117	13	58	107	0.34	0.44
CLU	rs11136000	t/C	184	177	28	88	68	23	82	72	0.72	1.00

MAF: minor allele frequency. HWE: Hardy-Weinberg equilibrium. ^#Two-tailed P value from Fisher’s exact test. Exact test against Hardy-Weinberg distribution (SNPStats).