Research Article

Relationships among Depression, Anxiety, Sleep, and Quality of Life in Patients with Parkinson’s Disease in Taiwan

Table 3

Differences in the participants’ characteristics according to the severity of depression and anxiety .

Depression severitypAnxiety severity p
Normal (1)Mild (2)Moderate (3)Severe (4)Normal (1)Mild (2)Moderate (3)Severe (4)

Sexn (%)85 (63.40)26 (19.40)12 (9.00)11 (8.20)42 (31.30)57 (42.50)24 (17.90)11 (8.20)
 Male85 (63.4%)63 (47.01)12 (8.96)4 (2.99)6 (4.48)31 (23.13)41 (30.60)9 (6.72)4 (2.99)
 Female49 (36.6%)22 (16.42)14 (10.44)8 (5.79)5 (3.73)11 (8.21)16 (11.94)15 (11.19)7 (5.22)
Onset age M ± SD
Current age65.82±9.03
Disease duration
 Post hoc(2) > ; (3) > (1)(3) > (1)
MMSE
UPDRS
 Post hoc(2) > (4) > (1); (3) > (1); (2) > (1)
UPDRS part I
 Post hoc(2) > (1); (4) > (1)(2) > (1); (3) > (1)
UPDRS part II
 Post hoc(2) > (1); (4) > (1); ;
UPDRS part III
UPDRS part VI
 Post hoc; ; ; (4) > (1)
H&Y stage
 Post hoc
PDSS-2
PDQ-39
 Post hoc(4) > (3); (4) > (2); (4) > (1); (4) > (2); (3) > (1); (3) > (2);
LEDD (mg)
 Post hoc; ;

M: mean; SD: standard deviation; MMSE: Mini-Mental State Examination; H&Y: Hoehn and Yahr scale; UPDRS: Unified Parkinson’s Disease Rating Scale; BAI: Beck Anxiety Inventory; BDI: Beck Depression Inventory; PDSS-2: Parkinson’s Disease Sleep Scale-2; PDQ-39: 39-item Parkinson’s Disease Questionnaire; LEDD: levodopa equivalent daily dosage. Chi-squared test with Fisher’s exact test; Bonferroni post hoc test; , , .