Levodopa-Induced Dyskinesia Is Related to Indirect Pathway Medium Spiny Neuron Excitotoxicity: A Hypothesis Based on an Unexpected Finding

Figure 2

Simplified representation of the corticostriatal processing unit in which cortical information leading to a movement is processed in an intracortical and (parallel) extrapyramidal fashion; (A) sensory input, (B) projections to brainstem and spinal cord, and (C) projection to and from ipsilateral and contralateral cortical areas. NS = nonspecific part; S = specific part.