Hepcidin Plays a Key Role in 6-OHDA Induced Iron Overload and Apoptotic Cell Death in a Cell Culture Model of Parkinson’s Disease

Table 1

The role of hepcidin knockdown in 6-OHDA induced oxidative damage measured by protein carbonyls () and intracellular iron measured by calcein quenching method ().

	Protein carbonyls (nmol/mg protein)	Calcein quenching (fluorescent units/mg protein)
Control siRNA	18.5 ± 2.9	112.4 ± 4.8
Hepcidin siRNA	8.9 ± 1.1	80.8 ± 6.2

Values are mean ± SEM; ; . Differences between two groups were based on Student’s -test; control siRNA: scrambled small interfering RNA; hepcidin siRNA: hepcidin small interfering RNA.