Transfection of the BDNF Gene in the Surviving Dopamine Neurons in Conjunction with Continuous Administration of Pramipexole Restores Normal Motor Behavior in a Bilateral Rat Model of Parkinson’s Disease

<div>The combined treatment (PPX + BDNF) restored gait. Gait recovery was estimated by the recovery of the stride length (a), stride velocity (b), and angle of the ankle (c) during the swing phase of gait. Data correspond to gait determination at 34 weeks after the dopaminergic lesion, two months after the end of the treatment. Pictures represent changes in the angle of the ankle during the swing. 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Data were analyzed by one-way ANOVA followed by Tukey post hoc test.</div>

Parkinson’s Disease

fig3

Figure 3

Figure 3: Transfection of the BDNF Gene in the Surviving Dopamine Neurons in Conjunction with Continuous Administration of Pramipexole Restores Normal Motor Behavior in a Bilateral Rat Model of Parkinson’s Disease 

Figure 3 | Transfection of the BDNF Gene in the Surviving Dopamine Neurons in Conjunction with Continuous Administration of Pramipexole Restores Normal Motor Behavior in a Bilateral Rat Model of Parkinson’s Disease 