Research Article

Perfluorochemical Liquid-Adenovirus Suspensions Enhance Gene Delivery to the Distal Lung

Figure 1

PFC liquid increases transduction efficiency in cell culture. (a) Representative fields of A549 cells transduced with rAd-CMVLacZ (MOI = 100 viral particles/cell) in either saline (Control, left) or PFC liquid (right) for 2 h (top) or 4 h (bottom) followed by X-gal staining. (b) Consecutive low-power fields were acquired under identical settings, and β-gal positive cells were enumerated manually. Values represent mean ± SD of 10 fields. * 𝑃 < 0 . 0 5 versus control.
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