The Immune Response and Its Therapeutic Modulation in Bronchiectasis

Table 3

Defects in immune system as risk factors for the development of bronchiectasis.

Common variable immunodeficiency (CVID)
IgG subclass deficiencies
Alteration in memory B cells
Defect in transporter associated with antigen presentation (TAP)
HLA deficiency
Hyper IgE syndrome
Secondary immune defect (post-chemotherapy)
Neutrophil oxidative burst deficiency
Chronic granulomatous disease inability of PMN to produce superoxides
Low mannose-binding lectin levels