Mannose-Binding Lectin Promoter Polymorphisms and Gene Variants in Pulmonary Tuberculosis Patients from Cantabria (Northern Spain)

Table 1

Allelic frequencies of MBL2 structural variants and promoter polymorphisms in healthy controls and patients with pulmonary tuberculosis.

	Structural variants				Promoter polymorphisms
	A	B	C	D	L	H	Y	X	P	Q
Controls
(n = 441)	0.782	0.143	0.008	0.067	0.655	0.345	0.760	0.240	0.815	0.195
PTB Patients
(n = 107)	0.836	0.131	0.009	0.023	0.678	0.322	0.776	0.224	0.757	0.243
𝑃 value^a,b				0.014
OR				0.33
(95% CI)				(0.13–0.84)

^aOnly D variant showed significant differences between the two groups. The rest of structural and promoter alleles did not show significant differences.
^bThe study had 74% power for detecting an odds ratio (OR) ≥ 2.