Research Article
Mannose-Binding Lectin Promoter Polymorphisms and Gene Variants in Pulmonary Tuberculosis Patients from Cantabria (Northern Spain)
Table 3
Frequencies of complete diplotypes in Spanish PTB patients and controls.
| | MBL2 diplotypes* | PTB patients
(%) | Controls
(%) | value | OR | (95% CI) |
| | LYQA/HYPA | 17 (15.9) | 54 (12.24) | 0.40 | 1.35 | (0.75–2.45) | | LYQA/LYPB | 10 (9.3) | 29 (6.58) | 0.43 | 1.46 | (0.69–3.11) | | LYQA/LYPA | 6 (5.6) | 19 (4.31) | 0.60 | 1.32 | (0.51–3.39) | | LYQA/LYQA | 3 (2.8) | 19 (4.31) | 0.59 | 0.64 | (0.19–2.20) | | LYQA/HYPD | 1 (0.9) | 10 (2.27) | 0.70 | 0.41 | (0.05–3.21) | | LYQA/LYQC | 0 (0) | 2 (0.45) | 1.0 | NA | NA | | LYQC/HYPD | 0 (0) | 1 (0.23) | 1.0 | NA | NA | | LXPA/HYPA | 15 (14.0) | 45 (10.20) | 0.34 | 1.43 | (0.77–2.69) | | LXPA/LYQA | 10 (9.3) | 53 (12.02) | 0.54 | 0.75 | (0.37–1.54) | | LXPA/LXPA | 7 (6.5) | 14 (3.17) | 0.15 | 2.14 | (0.84–5.43) | | LXPA/LYPB | 4 (3.7) | 31 (7.03) | 0.30 | 0.51 | (0.18–1.49) | | LXPA/HYPD | 3 (2.8) | 13 (2.95) | 1.0 | 0.95 | (0.27–3.39) | | LXPA/LYPA | 1 (0.9) | 10 (2.27) | 0.70 | 0.41 | (0.05–3.21) | | LXPA/LYQC | 1 (0.9) | 2 (0.45) | 0.48 | 2.07 | (0.19–23.05) | | HYPA/HYPA | 10 (9.3) | 38 (8.62) | 0.96 | 1.09 | (0.53–2.27) | | LYPB/HYPA | 8 (7.5) | 38 (8.62) | 0.88 | 0.86 | (0.39–1.89) | | LYPB/LYPB | 1 (0.9) | 7 (1.59) | 1.0 | 0.58 | (0.07–4.81) | | LYPB/LYQC | 1 (0.9) | 1 (0.23) | 0.35 | 4.15 | (0.26–66.90) | | LYPB/HYPD | 0 (0) | 9 (2.04) | 0.22 | NA | NA | | LYPA/HYPA | 4 (3.7) | 18 (4.08) | 1.0 | 0.91 | (1.30–2.75) | | LYPA/LYPB | 3 (2.8) | 4 (0.91) | 0.14 | 3.15 | (0.69–14.30) | | LYPA/LYPA | 1 (0.9) | 2 (0.45) | 0.48 | 2.07 | (0.19–23.05) | | LYPA/LYQC | 0 (0) | 1 (0.23) | 1.0 | NA | NA | | LYPA/HYPD | 1 (0.9) | 2 (0.45) | 0.48 | 2.07 | (0.19–23.05) | | HYPD/HYPA | 0 (0) | 14 (3.17) | 0.08 | NA | NA | | HYPD/HYPD | 0 (0) | 5 (1.13) | 0.59 | NA | NA |
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*Frequencies of the rest of combined diplotypes (LYQC/HYPA, LYQC/LYQC) were 0 in both groups.
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